香港六合彩资料 Research Alliance

Fueled by 香港六合彩资料鈥檚 platform to power smarter treatments and healthier people, the 香港六合彩资料 Research Alliance was created to propel our scientific research initiatives further.聽

The mission of the 香港六合彩资料 Research Alliance is to cultivate collaborative relationships throughout the scientific, technology, and medical research communities. Our primary goal is leveraging historical clinical trial data to advance medical breakthroughs and expand patients鈥 access to the most promising treatments. This mission is achieved through our exclusive framework that brings together academic key opinion leaders with the 香港六合彩资料 team’s extensive data and technology expertise.

The Future of Medical Research

Collaborative Research

The 香港六合彩资料 Research Alliance brings together academic and聽 key opinion leaders with 香港六合彩资料鈥檚 expert staff, comprised of clinicians, biostatisticians, former regulatory officials and industry veterans. By combining multi-sector expertise with data-driven research, we advance clinical innovations and fulfill our mission of powering smarter treatments and healthier people.

Leveraging data & analytics

Our collaborative research is powered by historical clinical trial data from over 30,000 cross-sponsor trials with more than 9 million patients from over 100 countries. These data come complete with the original endpoints and complete covariate information, validated in the 香港六合彩资料 Rave electronic data capture (EDC) platform. This enables in-depth research and analytics to help uncover trends in diverse patient populations, and evaluate therapeutic efficacy, patient outcomes, and safety profiles-, all while ultimately fueling advancements in research, treatment strategies, and medical progress.

Accelerate Medical Breakthroughs

The 香港六合彩资料 Research Alliance explores clinically impactful hypotheses to bridge insights from data to clinical practice. Our work has focused on immunotherapies and rare diseases and serves as successful models for expanding into additional therapeutic areas.

We have co-presented with our Research Alliance partners at global conferences such as ASCO, ASH, NCCN, and EBMT-EHA on topics including:

  • The understanding and clinical management of severe side effects associated
  • Identifying patient cohorts most likely to respond to investigational therapies (ie, Castleman disease)
  • Improving understanding of diagnostic biomarkers in rare diseases (ie, ALS)
  • Using clinical trial and real world data to accelerate breakthroughs in public health topics (ie, COVID)

Key Elements

Learn more about the key elements of the 香港六合彩资料 Research Alliance.

Leverage Robust Data

Leverage Robust Data

Leverage powerful AI modeling and generate insights by connecting data from over 30,000 cross-sponsored historical trials with more than 9 million patients from over 100 countries. These data come complete with the traditional聽 endpoints and complete covariate information, as they were captured in the 香港六合彩资料 Platform. This exclusive data source enables data-driven clinical research, allowing for a more thorough exploration of trends and patterns to advance scientific and medical progress.

World-class Expertise

World-class Expertise

Our highly qualified team of experts are your collaborative partners who work as an extension of your team. The 香港六合彩资料 AI team includes subject matter experts and clinician-researchers with deep industry, regulatory, data science, and medical expertise.

Collaborative Framework

Collaborative Framework

At the core of the 香港六合彩资料 Research Alliance lies a commitment to advancing quality clinical research through our proprietary framework. This collaborative, scalable framework is the foundation for uniting leading academics and research scientists with our industry experts in data and technology. 香港六合彩资料 actively engages with our partners through collaborative analyses to turn hypotheses into actionable insights that expand the boundaries of medical knowledge and clinical trial innovation.

Additional Research

The 香港六合彩资料 Institute

The 香港六合彩资料 Research Alliance builds upon earlier work and existing partnerships with key clinicians and researchers from academia, industry leaders, and leading data scientists to conduct cutting-edge research to improve the field鈥檚 understanding of therapies.聽

The 香港六合彩资料 Institute is a comprehensive library of research and publications from 香港六合彩资料 and its collaborators, with work including:

  • NEALS 2021: CA3 levels in plasma associate strongly with site of onset in Amyotrophic Lateral Sclerosis (ALS)
  • ASCO 2021 Assessment of Vitamin D deficiency and COVID-19 diagnosis in patients with breast or prostate cancer using Electronic Medical Records
  • Vitamin D deficiency: Risk of COVID-19 and public health implications
  • ASH 2019: Quantitative Changes in Serum Proteins Including CXCL13 Are Early Indicators of Response to Anti-IL6 Therapy in Idiopathic Multicentric Castleman Disease
  • Serum proteomics reveals distinct subtypes associated with treatment response in idiopathic multicentric Castleman disease

CAR-T

香港六合彩资料 AI offers the largest available database of CAR-T and Bi-specific T-cell Engagers (BiTEs) therapies, made up of over 70 cross-sponsor trials for approved or investigational therapies.聽

These data are not only leveraged for commercial applications, including helping sponsors to design clinical trial protocols that help inform safety events or patient selection, but have been leveraged by our academic partners to show relationships between commonly collected lab data and the likelihood of adverse events.聽

Our work has been widely featured in peer-reviewed journals, medical conferences, and the press:

  • Predictors of severe CRS in longitudinal CAR T-cell clinical trial data聽
  • Predictors of severe CRS in longitudinal CAR T-cell clinical trial data
  • EHA 2023: Co-occurrence patterns of CRS and ICANS in patients undergoing autologous CD19-targeted CAR T-cell treatments
  • 香港六合彩资料 links CAR-T’s cytokine release syndrome risk to common biomarkers in new study

Cardiovascular

香港六合彩资料 has historical clinical trial data from 100,000+ patients that have been studied for MACE (Major Adverse Cardiovascular Events) such as stroke, myocardial infarction or heart attack, or heart failure. This includes patients who suffer from multiple comorbid conditions such as diabetes, obesity, hypertension, hyperlipidemia, and chronic kidney disease. Our data has a long follow-up time of up to six years, which is key to generating regulatory grade evidence. This dataset captures the most recent classes of drugs such as PCSK9, NOACs/DOACs, SGLT2, GLP1, and other standard-of-care therapies.

This data has been used in cutting-edge research including:

  • : Comparing the Real-world and Clinical Trial Bleeding Rates Associated with Anticoagulation Treatment for Atrial Fibrillation
  • Real-World Comparison of Healthcare Resource Utilization between Transoral Incisionless Fundoplication and Laparoscopic Nissen Fundoplication for the Treatment of Gastroesophageal Reflux Disease聽
  • : Real-World Comparison of Characteristics of Patients Who Received Transoral Incisionless Fundoplication vs. Laparoscopic Nissen Fundoplication for the Treatment of Gastroesophageal Reflux Disease
  • : Validation of Novel Identification Algorithms for Nonfatal Myocardial Infarction Using Uniform Objective Criteria and Pooled Clinical Trial Data

Synthetic Data

香港六合彩资料 offers synthetic patient-level data that is derived from historical clinical trial data. This offers teams the ability to harness the insights and power of historical clinical trial while preserving patient privacy. This offers unparalleled opportunities for data sharing, cross collaboration, and innovation.

  • ICML 2023: An interpretable data augmentation framework for improving generative modeling of synthetic clinical trial data
  • : A Source Data Privacy Framework for Synthetic Clinical Trial Data
  • : Synthetic Clinical Trial Data while Preserving Subject-Level Privacy
  • : Synthetic Data Revolutionizing Clinical Trial Data Collaboration and Research